If found on a known site where other like items were found, then yes, it could be a Bead. Found in a creek with no association to any other known sites or Beads, then it's more than likely natural and may be an eroded Crinoid. I saw several Crinoid Bead Necklaces years ago that were found just north of Lucasville Ohio by Harold Young. He told me that back in the 40's the Scioto River came up out of it's banks and washed down through the fields uncovering several graves. A friend of his helped him rebury all the bones but not until after they gathered up all the artifacts, which included over 500 Crinoid Beads that he restrung into several Necklaces. They had an auction after he died and these went really high, like over $1200 for all of them. I have a few I have found on Ft Ancient sites that I am sure were Beads, but I also find them in all of our creeks that are just naturally polished like yours.