Sure. Portland area is out, there ain't no gold there. Next south is the Santiam, I've only been up there once and couldn't find a speck if my life depended on it, LOL! At Jawbone flats up there is where the gold was found. If you remember the Opal creek tree sitters and all that turmoil, thats where they are too. Good place to stay away from.
Next south is Quartzville. And this is gonna be a little hard to describe, cause its a loooong corridor. Just where Quartzville creek hits the slackwater of Green Peter Reservoir is where I've done the best. The slackwater level changes, of course, when they are either holding back or letting go of water out of Green Peter. So keep an eye out for a little turn out next to the road on the water side. Maybe big enough to hold about ten cars. There's a natural dike there that now looks like two huge boulders on either side of the creek. (Its actually the remains of a wall of rock that the water has worn its way through)
If you park in this little turnout, you're actually parking on hardpan thats full of pea size chunks of gold. Go down by the creek here and chip away at the hard pan, screen it carefully to break up the clay and pan it down. Its slow going, this stuff is like cement, but it does have good gold in it.
Also, up at the top of the corridor, above Yellowbottom, is a bridge. Just downstream from the bridge you can do alright if you find the right cracks to dig out. Take a metal rake with you (the stiff kind with tines) and rake all the loose stuff out of the way, it'll speed things up quite a bit.
I haven't found squat at Yellowbottom, thats where the locals will send you. Lots of tales about that place, but it musta been hit pretty doggone hard over the years....
Its a pretty well civilized place, but do be careful up there if there ain't many people around. I once had to pack a guy out who broke a bunch of ribs when he took a nasty fall. Me and Dad were the only two around for miles. He woulda been a sorry sucker! So don't be in a hurry for anything and look where you're stepping.
Best route in is to go to Sweethome on the freeway and then head east and north on 22 to Quartzville creek road. Don't try the backroads this time of year, especially the ones coming in from the north.
Good luck up there, let us know how you do!
(BTW- Quartzville, in my experience, is either hit or miss. You'll either do good, or not much at all. Its pretty spotty up there)
. Treasure chest full of gold nuggets perhaps?
? 
I'll have to do some more research on the immigrant camp just from walking around the mouth of the creek it sure is tuff to tell where their camp was. Did some MD'n but only found new coins and some newer iron trash. We gave it a heck of a shot though!! 
