Your library or historical society would be a good start to look for locations that once had homesteads in your area. Failing that some signs to look for where there may have been a root cellar would be depressions in the ground either square or rectangular that are of a size that a house could have been. Look also for rocks, stones that would out line the cellar (may be moss covered ) and there could also be small trees, plants growing from this moss now.
Some of these sites may be filled in from erosion and would appear as a mound or some could be filled with water with just the outer stones showing...Detecting around these may produce old tools, buckets etc that are home related which will tell that you are in the right spot...... Good luck with you hunt.....